Article
Maintenance of Membrane Integrity and Permeability Depends on a Patched-Related Protein in Caenorhabditis elegans.
Genetics - 1 Apr 2016
Choi Myung-Kyu, Son Sangwon, Hong Mingi, Choi Min Sung, Kwon Jae Young, Lee Junho
Abstract excerpt
Membrane integrity is critical for cell survival, defects of which cause pathological symptoms such as metabolic diseases. In this study, we used ethanol sensitivity of the nematode Caenorhabditis elegans to identify genetic factors involved in membrane integrity. InC. elegans, acute exposure to a high concentration (7% v/v) of ethanol changes membrane permeability, as measured by propidium iodide staining, and...
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