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Article

Heterochromatin protein 1 is required for correct chromosome segregation in Drosophila embryos.

Journal of cell science - 1 Apr 1995

Kellum R, Alberts B M

Abstract excerpt

Heterochromatin protein 1 is associated with centromeric heterochromatin in Drosophila, mice, and humans. Loss of function mutations in the gene encoding heterochromatin protein 1 in Drosophila, Suppressor of variegation2-5, decrease the mosaic repression observed for euchromatic genes that have...

Topics

Alleles
Animals
Chromobox Protein Homolog 5
Chromosomal Proteins, Non-Histone
Crosses, Genetic
Drosophila
Embryo, Nonmammalian
Female
Fluorescent Antibody Technique
Genes, Insect
Genes, Lethal
Genes, Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Mice

Phenotype

Prophase

Source

Identifiers

PMID: 7615663
DOI: 10.1242/jcs.108.4.1419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7615663-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Heterochromatin protein 1 is required for correct chromosome segregation in Drosophila embryos.PMID 7615663Read ↗

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