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Article

A Fully Human Inhibitory Monoclonal Antibody to the Wnt Receptor RYK

18 Sept 2013

Abstract excerpt

RYK is an unusual member of the receptor tyrosine kinase (RTK) family that is classified as a putative pseudokinase. RYK regulates fundamental biological processes including cell differentiation, migration and target selection, axon outgrowth and pathfinding by transducing signals across the plasma membrane in response to the high affinity binding of Wnt family ligands to its extracellular Wnt inhibitory factor...

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Share to Monoclonal and Polyclonal Antibodies Research
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PMID: 24058687
DOI: 10.1371/journal.pone.0075447

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