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Article

Receptor tyrosine kinases: from biology to pathology.

Journal of receptor and signal transduction research - 1 Dec 2011

Choura Mouna, Rebaï Ahmed

Abstract excerpt

Receptor tyrosine kinases (RTKs) are transmembrane proteins involved in the control of fundamental cellular processes in metazoans. RTKs possess a general structure that includes an extracellular domain, a transmembrane domain and a highly conserved tyrosine kinase domain. RTKs are classified according to their variable extracellular ligand-binding domain. Studies of human RTK members have yielded a wealth of...

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PMID: 22040163
DOI: 10.3109/10799893.2011.625425

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