Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ERG9 and COQ1 disruption reveals isoprenoids biosynthesis is closely related to mitochondrial function in Saccharomyces cerevisiae.

Integrative biology : quantitative biosciences from nano to macro - 1 Oct 2013

Huang Beibei, Guo Jing, Sun Lianna, Chen Wansheng

Abstract excerpt

Understanding in vivo regulation of isoprenoid biosynthesis is important for identifying strategies to improve carbon fluxes to desirable endproducts. To study the relevance of gene functions, substrate availability, metabolic flux, and the energetics of resource utilization for isoprenoids biosynthesis, Saccharomyces cerevisiae was co-engineered with endogenous deregulated erg9 and/or coq1 and exogenous plant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Regulation, Bacterial
Share to Gene Silencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitochondria

Share to Mutation

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Terpenes

Share to Ubiquinone

Source

Identifiers

PMID: 24056878
DOI: 10.1039/c3ib40063h

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ERG9 and COQ1 disruption reveals isoprenoids biosynthesis is closely related to mitochondrial function in Saccharomyces cerevisiae.PMID 24056878Read ↗

The wide-ranging phenotypes of ergosterol biosynthesis mutants, and implications for microbial cell factories.Semantic proximity Read ↗

Enhance production of diterpenoids in yeast by overexpression of the fused enzyme of ERG20 and its mutant mERG20.Semantic proximity Read ↗

Altered sterol metabolism in budding yeast affects mitochondrial iron-sulfur (Fe-S) cluster synthesis.Semantic proximity Read ↗

Coenzyme Q10 deficiencies: pathways in yeast and humans.Semantic proximity Read ↗

Efficient production of (S)-limonene and geraniol in Saccharomyces cerevisiae through the utilization of an Erg20 mutant with enhanced GPP accumulation capability.Semantic proximity Read ↗

The use of mutants and inhibitors to study sterol biosynthesis in plantsSemantic proximity Read ↗

Establishing Saccharomyces cerevisiae as a host for renewable acrylic acid production.Semantic proximity Read ↗

Overexpression or Deletion of Ergosterol Biosynthesis Genes Alters Doubling Time, Response to Stress Agents, and Drug Susceptibility in Saccharomyces cerevisiaeSemantic proximity Read ↗

Optimization of central carbon metabolism by Warburg effect of human cancer cell improves triterpenes biosynthesis in yeastSemantic proximity Read ↗

The genetics and molecular genetics of terpene and sterol origami.Semantic proximity Read ↗

Genomic reconstruction to improve bioethanol and ergosterol production of industrial yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Biosynthesis of cannabinoid precursor olivetolic acid by overcoming rate-limiting steps in genetically engineered <i>Yarrowia lipolytica</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.