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Biosynthesis of cannabinoid precursor olivetolic acid by overcoming rate-limiting steps in genetically engineered <i>Yarrowia lipolytica</i>

2021-06-10

Abstract excerpt

Natural products acting on our central nervous systems are in utmost demand to fight against pain and mental disorders. Cannabinoids (CBDs) are proven neuroactive agents to treat anxiety, depression, chronic pain diseases, seizure, strokes and neurological disorders. The scarcity of the hemp-sourced CBD products and the prohibitive manufacturing cost limit the wide application of CBDs. Yeast metabolic engineering...

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Literature Corpus work
fd06f338-d763-592d-9707-ce3647034a8d
DOI
10.1101/2021.06.10.447928
Open publication

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