Article
Efficient production of (S)-limonene and geraniol in Saccharomyces cerevisiae through the utilization of an Erg20 mutant with enhanced GPP accumulation capability.
Metabolic engineering - 1 May 2024
Bernard Armand, Cha Seungwoo, Shin Hyesoo, Lee Daeyeol, Hahn Ji-Sook
Abstract excerpt
Monoterpenes and monoterpenoids such as (S)-limonene and geraniol are valuable chemicals with a wide range of applications, including cosmetics, pharmaceuticals, and biofuels. Saccharomyces cerevisiae has proven to be an effective host to produce various terpenes and terpenoids. (S)-limonene and geraniol are produced from geranyl pyrophosphate (GPP) through the enzymatic actions of limonene synthase (LS) and...
Topics
- Saccharomyces cerevisiae
- Limonene
- Terpenes
- Acyclic Monoterpenes
- Metabolic Engineering
- Mutation
- Saccharomyces cerevisiae Proteins
- Polyisoprenyl Phosphates
- Diterpenes
- Diphosphates