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Article

Coenzyme Q10 deficiencies: pathways in yeast and humans.

Essays in biochemistry - 20 Jul 2018

Awad Agape M, Bradley Michelle C, Fernández-Del-Río Lucía, Nag Anish, Tsui Hui S, Clarke Catherine F

Abstract excerpt

Coenzyme Q (ubiquinone or CoQ) is an essential lipid that plays a role in mitochondrial respiratory electron transport and serves as an important antioxidant. In human and yeast cells, CoQ synthesis derives from aromatic ring precursors and the isoprene biosynthetic pathway. Saccharomyces cerevisiae coq mutants provide a powerful model for our understanding of CoQ biosynthesis. This review focusses on the...

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Identifiers

PMID: 29980630
DOI: 10.1042/EBC20170106
PMCID: PMC6056717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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