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Establishing Saccharomyces cerevisiae as a host for renewable acrylic acid production.

Microbial cell factories - 4 Mar 2026

Eisentraut Leon, Li Xiaowei, Chen Yun

Abstract excerpt

Acrylic acid (AA) is an important industrial chemical with a wide range of applications and growing market demand. To explore sustainable production routes, we investigated Saccharomyces cerevisiae as a host organism for direct fermentative production of AA. We first assessed the native tolerance of the host to AA and employed adaptive laboratory evolution to obtain strains with improved phenotypes. Whole-genome...

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Identifiers

PMID: 41781959
DOI: 10.1186/s12934-026-02974-3
PMCID: PMC13067684

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