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Article

Genetic mapping with multiple levels of phenotypic information reveals determinants of lymphocyte glucocorticoid sensitivity.

American journal of human genetics - 3 Oct 2013

Maranville Joseph C, Baxter Shaneen S, Witonsky David B, Chase Meredith A, Di Rienzo Anna

Abstract excerpt

Clinical response to glucocorticoids, steroid hormones widely used as pharmaceuticals, varies extensively in that many individuals (∼30%) show a weak response to treatment. Although little is known about the molecular basis of this variation, regulatory polymorphisms are likely to play a key role given that glucocorticoids act largely through activation of a transcription factor, the glucocorticoid receptor. In...

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Share to Glucocorticoids
Share to Leukocytes, Mononuclear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Quantitative Trait Loci

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Source

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Identifiers

PMID: 24055111
DOI: 10.1016/j.ajhg.2013.08.005
PMCID: PMC3791266

Genes

RBMS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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