Article
Glucocorticoid sensitivity in health and disease.
Nature reviews. Endocrinology - 1 Nov 2013
Quax Rogier A, Manenschijn Laura, Koper Jan W, Hazes Johanna M, Lamberts Steven W J, van Rossum Elisabeth F C, Feelders Richard A
Abstract excerpt
Glucocorticoids regulate many physiological processes and have an essential role in the systemic response to stress. For example, gene transcription is modulated by the glucocorticoid-glucocorticoid receptor complex via several mechanisms. The ultimate biologic responses to glucocorticoids are determined by not only the concentration of glucocorticoids but also the differences between individuals in...
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