Article
Card15 mutations and gastric cancer in a Portuguese population.
Scandinavian journal of gastroenterology - 1 Oct 2013
Freire Paulo, Figueiredo Pedro, Cardoso Ricardo, Donato Maria M, Sá Anabela, Portela Francisco, Romãozinho José M, Sofia Carlos
Abstract excerpt
BACKGROUND. CARD15 is involved in the innate immune response and mutations of this gene have been linked with increased risk of Crohn's disease and colorectal cancer. The relation between CARD15 mutations and gastric cancer (GC) remains controversial. AIMS. To assess whether CARD15 mutations are risk factors for GC in Portugal and whether there are genotype-phenotype correlations in these patients. METHODS. The 3...
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