Article
CARD15 mutations in Dutch familial and sporadic inflammatory bowel disease and an overview of European studies.
European journal of gastroenterology & hepatology - 1 Jun 2007
van der Linde Klaas, Boor Patrick P C, Houwing-Duistermaat Jeanine J, Crusius Bart J A, Wilson Paul J H, Kuipers Ernst J, de Rooij Felix W M
Abstract excerpt
OBJECTIVES: The single nucleotide variations R702W, G908R and L1007fs in the CARD15 gene have been found to be independently associated with Crohn's disease. The aim of this study was to evaluate the prevalence of these gene variations in Dutch multiple inflammatory bowel disease-affected families, in sporadic inflammatory bowel disease patients and in healthy controls. METHODS: Dutch Caucasians from multiple...
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