Article
Gastroduodenal Crohn's disease is associated with NOD2/CARD15 gene polymorphisms, particularly L1007P homozygosity.
Digestive diseases and sciences - 1 Dec 2005
Mardini Houssam E, Gregory Kalvin J, Nasser Munira, Selby Lisbeth, Arsenescu Razvan, Winter Trevor A, de Villiers Willem J S
Abstract excerpt
Limited data exist on the specific association between gastroduodenal Crohn's disease (GDCD) and NOD2/CARD15 gene polymorphisms. The aim of this study was to assess the association between NOD2 polymorphisms and GDCD, and to assess the specific association between each of the 3 major allelic variants G908R, L1007P, and R702W and the clinical features of Crohn's disease. We retrospectively reviewed the records of...
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