Article
CARD15 gene polymorphisms in Serbian patients with Crohn's disease: genotype-phenotype analysis.
European journal of gastroenterology & hepatology - 1 Oct 2008
Protic Marijana B, Pavlovic Sonja T, Bojic Daniela Z, Krstic Miodrag N, Radojicic Zoran A, Tarabar Dino K, Stevanovic Ana Z, Karan Djurasevic Teodora Z, Godjevac Mina V, Svorcan Petar V, Dapcevic Branka D, Jojic Njegica Z
Abstract excerpt
OBJECTIVE: Genetic heterogeneity and incomplete phenotype penetrance complicate genetic analysis of Crohn's disease (CD). Studies in western Europe have shown that CARD15 polymorphisms increase susceptibility to CD, but frequencies vary within different European populations. The aim here was to evaluate the prevalence of CARD15 mutations and their phenotypic correlation in a Serbian population. MATERIALS AND...
Topics
- Adolescent
- Adult
- Age of Onset
- Aged
- Case-Control Studies
- Chi-Square Distribution
- Colitis, Ulcerative
- Crohn Disease
- Female
- Follow-Up Studies