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Article

The Role of Type III Interferons in Hepatitis C Virus Infection and Therapy

1 Jan 2017

Abstract excerpt

The human interferon (IFN) response is a key innate immune mechanism to fight virus infection. IFNs are host-encoded secreted proteins, which induce IFN-stimulated genes (ISGs) with antiviral properties. Among the three classes of IFNs, type III IFNs, also called IFN lambdas (IFNLs), are an essential component of the innate immune response to hepatitis C virus (HCV). In particular, human polymorphisms in IFNL...

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PMID: 28255563
DOI: 10.1155/2017/7232361

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