Article
Mitochondrial haplotypes associated with biomarkers for Alzheimer's disease.
PloS one - 1 Jan 2013
Ridge Perry G, Koop Andre, Maxwell Taylor J, Bailey Matthew H, Swerdlow Russell H, Kauwe John S K, Honea Robyn A
Abstract excerpt
Various studies have suggested that the mitochondrial genome plays a role in late-onset Alzheimer's disease, although results are mixed. We used an endophenotype-based approach to further characterize mitochondrial genetic variation and its relationship to risk markers for Alzheimer's disease. We analyzed longitudinal data from non-demented, mild cognitive impairment, and late-onset Alzheimer's disease...
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