Article
Analysis of European mitochondrial haplogroups with Alzheimer disease risk.
Neuroscience letters - 15 Jul 2004
van der Walt Joelle M, Dementieva Yulia A, Martin Eden R, Scott William K, Nicodemus Kristin K, Kroner Charles C, Welsh-Bohmer Kathleen A, Saunders Ann M, Roses Allen D, Small Gary W, Schmechel Donald E, Murali Doraiswamy P, Gilbert John R, Haines Jonathan L, Vance Jeffery M, Pericak-Vance Margaret A
Abstract excerpt
We examined the association of mtDNA variation with Alzheimer disease (AD) risk in Caucasians (989 cases and 328 controls) testing the effect of individual haplogroups and single nucleotide polymorphisms (SNPs). Logistic regression analyses were used to assess risk of haplogroups and SNPs with AD in both main effects and interaction models. Males classified as haplogroup U showed an increase in risk (OR = 2.30;...
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