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Article

Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress.

PloS one - 1 Jan 2013

Farkas Carlos, Martins Carla P, Escobar David, Hepp Matias I, Castro Ariel F, Evan Gerard, Gutiérrez José L, Warren Robert, Donner David B, Pincheira Roxana

Abstract excerpt

SALL2- a member of the Spalt gene family- is a poorly characterized transcription factor found deregulated in various cancers, which suggests it plays a role in the disease. We previously identified SALL2 as a novel interacting protein of neurotrophin receptors and showed that it plays a role in neuronal function, which does not necessarily explain why or how SALL2 is deregulated in cancer. Previous evidences...

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Identifiers

PMID: 24040083
DOI: 10.1371/journal.pone.0073817
PMCID: PMC3765348

Genes

SALL2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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