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Article

Activation of p53 transcriptional activity by SMRT: a histone deacetylase 3-independent function of a transcriptional corepressor.

Molecular and cellular biology - 1 Apr 2014

Adikesavan Anbu Karani, Karmakar Sudipan, Pardo Patricia, Wang Liguo, Liu Shuang, Li Wei, Smith Carolyn L

Abstract excerpt

The silencing mediator of retinoic acid and thyroid hormone receptors (SMRT) is an established histone deacetylase 3 (HDAC3)-dependent transcriptional corepressor. Microarray analyses of MCF-7 cells transfected with control or SMRT small interfering RNA revealed SMRT regulation of genes involved...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24449765
DOI: 10.1128/MCB.01216-13
PMCID: PMC3993559

Genes

HDAC3
GPS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24449765-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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