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Article

Quality score based identification and correction of pyrosequencing errors.

PloS one - 1 Jan 2013

Iyer Shyamala, Bouzek Heather, Deng Wenjie, Larsen Brendan, Casey Eleanor, Mullins James I

Abstract excerpt

Massively-parallel DNA sequencing using the 454/pyrosequencing platform allows in-depth probing of diverse sequence populations, such as within an HIV-1 infected individual. Analysis of this sequence data, however, remains challenging due to the shorter read lengths relative to that obtained by Sanger sequencing as well as errors introduced during DNA template amplification and during pyrosequencing. The ability...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24039850
DOI: 10.1371/journal.pone.0073015
PMCID: PMC3764156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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