Article
PyroHMMsnp: an SNP caller for Ion Torrent and 454 sequencing data.
Nucleic acids research - 1 Jul 2013
Zeng Feng, Jiang Rui, Chen Ting
Abstract excerpt
Both 454 and Ion Torrent sequencers are capable of producing large amounts of long high-quality sequencing reads. However, as both methods sequence homopolymers in one cycle, they both suffer from homopolymer uncertainty and incorporation asynchronization. In mapping, such sequencing errors could...
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