Article
VirVarSeq: a low-frequency virus variant detection pipeline for Illumina sequencing using adaptive base-calling accuracy filtering.
Bioinformatics (Oxford, England) - 1 Jan 2015
Verbist Bie M P, Thys Kim, Reumers Joke, Wetzels Yves, Van der Borght Koen, Talloen Willem, Aerssens Jeroen, Clement Lieven, Thas Olivier
Abstract excerpt
MOTIVATION: In virology, massively parallel sequencing (MPS) opens many opportunities for studying viral quasi-species, e.g. in HIV-1- and HCV-infected patients. This is essential for understanding pathways to resistance, which can substantially improve treatment. Although MPS platforms allow in-...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.