Article

MERIT: a Mutation Error Rate Identification Toolkit for Ultra-deep Sequencing Applications

2017-09-04

Abstract excerpt

Rapid progress in high-throughput sequencing (HTS) has enabled the molecular characterization of mutational landscapes in heterogeneous populations and has improved our understanding of clonal evolution processes. Analyzing the sensitivity of detecting genomic mutations in HTS requires comprehensive profiling of sequencing artifacts. To this end, we introduce MERIT, designed for in-depth quantification of erroneou...

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Literature Corpus work: 9c68f10a-0bd2-5537-b5de-5d5ab2660450
DOI: 10.1101/184291

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