Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-nucleotide polymorphism C3435T in the ABCB1 gene is associated with opioid consumption in postoperative pain.

Pain medicine (Malden, Mass.) - 1 Dec 2013

Candiotti Keith, Yang Zhe, Xue Lihua, Zhang Yanping, Rodriguez Yiliam, Wang Liyong, Hao Shuangling, Gitlin Melvin

Abstract excerpt

BACKGROUND: ABCB1 is a major determinant of opioid bioavailability; however, no previous studies have provided positive evidence of an association between single-nucleotide polymorphisms (SNPs) of ABCB1 and opioid usage in acute pain management. The aim of this study was to test the association between the functional SNP C3435T in ABCB1 and opioid consumption in postoperative pain in patients undergoing a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Analgesics, Opioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Share to Nephrectomy

Share to Pain, Postoperative

Share to Polymorphism, Single Nucleotide

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 24034787
DOI: 10.1111/pme.12226

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-nucleotide polymorphism C3435T in the ABCB1 gene is associated with opioid consumption in postoperative pain.PMID 24034787Read ↗

Association of Single-Nucleotide Polymorhism C3435T in the ABCB1 Gene with Opioid Sensitivity in Treatment of Postoperative Pain.Semantic proximity Read ↗

Catechol-o-methyltransferase polymorphisms predict opioid consumption in postoperative pain.Semantic proximity Read ↗

Gene polymorphisms of OPRM1 A118G and ABCB1 C3435T may influence opioid requirements in Chinese patients with cancer pain.Semantic proximity Read ↗

Effects of genetic polymorphisms of OPRM1, ABCB1, CYP3A4/5 on postoperative fentanyl consumption in Korean gynecologic patients.Semantic proximity Read ↗

The impact of genetic variation on sensitivity to opioid analgesics in patients with postoperative pain: a systematic review and meta-analysis.Semantic proximity Read ↗

Effect of CYP3A4*18B polymorphisms and interactions with OPRM1 A118G on postoperative fentanyl requirements in patients undergoing radical gastrectomy.Semantic proximity Read ↗

Experimental Evaluation of ABCB1 C3435T (rs1045642) Gene Polymorphism and Its Association with Postoperative Analgesia in Hip Replacement Surgery.Semantic proximity Read ↗

OPRM1 and ABCB1 Polymorphisms and Their Effect on Postoperative Pain Relief With PiritramideSemantic proximity Read ↗

ABCB1 genetic polymorphisms affect opioid requirement by altering function of the intestinal P-glycoprotein.Semantic proximity Read ↗

[How can we cope with wide individual variations in pain intensity and opioid requirements after surgery?].Semantic proximity Read ↗

Association of single nucleotide polymorphisms of ABCB1, OPRM1 and COMT with pain perception in cancer patients.Semantic proximity Read ↗

Effect of Pregnane X Receptor*1B genetic polymorphisms on postoperative analgesia with fentanyl in Chinese patients undergoing gynecological surgery.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.