Article
Association of single nucleotide polymorphisms of ABCB1, OPRM1 and COMT with pain perception in cancer patients.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban - 1 Oct 2015
Wang Xu-Shi, Song Hai-Bin, Chen Si, Zhang Wei, Liu Jia-Qi, Huang Chao, Wang Hao-Ran, Chen Yuan, Chu Qian
Abstract excerpt
Pain perception is influenced by multiple factors. The single nucleotide polymorphisms (SNPs) of some genes were found associated with pain perception. This study aimed to examine the association of the genotypes of ABCB1 C3435T, OPRM1 A118G and COMT V108/158M (valine 108/158 methionine) with pain perception in cancer patients. We genotyped 146 cancer pain patients and 139 cancer patients without pain for ABCB1...
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