Article
Accurate and fast multiple-testing correction in eQTL studies.
American journal of human genetics - 4 Jun 2015
Sul Jae Hoon, Raj Towfique, de Jong Simone, de Bakker Paul I W, Raychaudhuri Soumya, Ophoff Roel A, Stranger Barbara E, Eskin Eleazar, Han Buhm
Abstract excerpt
In studies of expression quantitative trait loci (eQTLs), it is of increasing interest to identify eGenes, the genes whose expression levels are associated with variation at a particular genetic variant. Detecting eGenes is important for follow-up analyses and prioritization because genes are the main entities in biological processes. To detect eGenes, one typically focuses on the genetic variant with the minimum...
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