Article
Predicting Gene Regulatory Interactions Using Natural Genetic Variation.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2023
John Maura, Grimm Dominik, Korte Arthur
Abstract excerpt
Genome-wide association studies (GWAS) are a powerful tool to elucidate the genotype-phenotype map. Although GWAS are usually used to assess simple univariate associations between genetic markers and traits of interest, it is also possible to infer the underlying genetic architecture and to predict gene regulatory interactions. In this chapter, we describe the latest methods and tools to perform GWAS by...
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