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Article

Nkx genes are essential for maintenance of ventricular identity.

Development (Cambridge, England) - 1 Oct 2013

Targoff Kimara L, Colombo Sophie, George Vanessa, Schell Thomas, Kim Seok-Hyung, Solnica-Krezel Lilianna, Yelon Deborah

Abstract excerpt

Establishment of specific characteristics of each embryonic cardiac chamber is crucial for development of a fully functional adult heart. Despite the importance of defining and maintaining unique features in ventricular and atrial cardiomyocytes, the regulatory mechanisms guiding these processes are poorly understood. Here, we show that the homeodomain transcription factors Nkx2.5 and Nkx2.7 are necessary to...

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Share to Heart Atria
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Share to Homeobox Protein Nkx-2.5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Myocytes, Cardiac

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Source

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Identifiers

PMID: 24026123
DOI: 10.1242/dev.095562
PMCID: PMC3787760

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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