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Article

Human dopamine transporter gene: differential regulation of 18-kb haplotypes.

Pharmacogenomics - 1 Sept 2013

Zhao Ying, Xiong Nian, Liu Yang, Zhou Yanhong, Li Nuomin, Qing Hong, Lin Zhicheng

Abstract excerpt

AIM: Since previous functional studies of short haplotypes and polymorphic sites of SLC6A3 have shown variant-dependent and drug-sensitive promoter activity, this study aimed to understand whether a large SLC6A3 regulatory region, containing these small haplotypes and polymorphic sites, can display haplotype-dependent promoter activity in a drug-sensitive and pathway-related manner. MATERIALS & METHODS: By...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

Share to Regulatory Sequences, Nucleic Acid

Source

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Identifiers

PMID: 24024899
DOI: 10.2217/pgs.13.141
PMCID: PMC3870138

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