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Article

The dopamine transporter gene SLC6A3: multidisease risks.

Molecular psychiatry - 1 Feb 2022

Reith Maarten E A, Kortagere Sandhya, Wiers Corinde E, Sun Hui, Kurian Manju A, Galli Aurelio, Volkow Nora D, Lin Zhicheng

Abstract excerpt

The human dopamine transporter gene SLC6A3 has been consistently implicated in several neuropsychiatric diseases but the disease mechanism remains elusive. In this risk synthesis, we have concluded that SLC6A3 represents an increasingly recognized risk with a growing number of familial mutants associated with neuropsychiatric and neurological disorders. At least five loci were related to common and severe...

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Identifiers

PMID: 34650206
DOI: 10.1038/s41380-021-01341-5
PMCID: PMC9008071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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