Article
Common human 5' dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo.
Cellular and molecular neurobiology - 1 Jan 2000
Drgon Tomas, Lin Zhicheng, Wang Gene-Jack, Fowler Joanna, Pablo Johnfn, Mash Deborah C, Volkow Nora, Uhl George R
Abstract excerpt
1. Individuals display significant differences in their levels of expression of the dopamine transporter (DAT; SLC6A3). These differences in DAT are strong candidates to contribute to individual differences in motor, mnemonic and reward functions. To identify "cis"-acting genetic mechanisms for these individual differences, we have sought variants in 5' aspects of the human DAT gene and identified the haplotypes...
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