Article
Effects of HTR1B 3' region polymorphisms and functional regions on gene expression regulation.
BMC genetics - 20 Jul 2020
Xia Xi, Ding Mei, Xuan Jin-Feng, Xing Jia-Xin, Pang Hao, Yao Jun, Wu Xue, Wang Bao-Jie
Abstract excerpt
BACKGROUND: The HTR1B gene encodes the 5-hydroxytryptamine (5-HT1B) receptor, which is involved in a variety of brain activities and mental disorders. The regulatory effects of non-coding regions on genomic DNA are one of many reasons for the cause of genetic-related diseases. Post-transcriptional regulation that depends on the function of 3' regulatory regions plays a particularly important role. This study...
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