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Article

HIV subtype influences HLA-B*07:02-associated HIV disease outcome.

AIDS research and human retroviruses - 1 May 2014

Kløverpris Henrik N, Adland Emily, Koyanagi Madoka, Stryhn Anette, Harndahl Mikkel, Matthews Philippa C, Shapiro Roger, Walker Bruce D, Ndung'u Thumbi, Brander Christian, Takiguchi Masafumi, Buus Søren, Goulder Philip

Abstract excerpt

Genetic polymorphisms within the MHC encoding region have the strongest impact on HIV disease progression of any in the human genome and provide important clues to the mechanisms of HIV immune control. Few analyses have been undertaken of HLA alleles associated with rapid disease progression. HLA-B*07:02 is an HLA class I molecule that is prevalent in most populations worldwide and that has previously been...

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Identifiers

PMID: 24010680
DOI: 10.1089/AID.2013.0197
PMCID: PMC4010166

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