Article
Association of serum components of the GH-IGFs-IGFBPs system with GHR-exon 3 polymorphism in normal and idiopathic short stature children.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Dec 2013
Ballerini María Gabriela, Domené Horacio Mario, Scaglia Paula, Martínez Alicia, Keselman Ana, Jasper Héctor Guillermo, Ropelato María Gabriela
Abstract excerpt
OBJECTIVE: To investigate the possible association of circulating components of GH-IGFs-IGFBPs system with the GHR-exon 3 genotype in normal and idiopathic short stature (ISS) children. DESIGN: Descriptive, cross-sectional study in normal and ISS children. SUBJECTS AND METHODS: 192 normal and 81 ISS children (age: 5-17 years) were included. Serum IGF-I, IGFBP3, ALS and GHBP levels were measured. GHR-exon 3...
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