Article
Characterizing short stature by insulin-like growth factor axis status and genetic associations: results from the prospective, cross-sectional, epidemiogenetic EPIGROW study.
The Journal of clinical endocrinology and metabolism - 1 Jun 2013
Clayton Peter, Bonnemaire Mireille, Dutailly Pascale, Maisonobe Pascal, Naudin Laurent, Pham Emmanuel, Zhang Zhidong, Grupe Andrew, Thiagalingam Arunthathi, Denèfle Patrice
Abstract excerpt
CONTEXT: Serum IGF-I levels are often low in patients with short stature (SS) without defined etiology. Hence, genetic investigations have focused on the GH-IGF-I axis. OBJECTIVE: Our objectives were to characterize IGF-I axis status and search for a broader range of genetic associations in children with SS and normal GH. DESIGN AND SETTING: We conducted a prospective, cross-sectional, epidemiogenetic...
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