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Article

Exon 3-deleted genotype of growth hormone receptor (GHRd3) positively influences IGF-1 increase at generation test in children with idiopathic short stature.

Clinical endocrinology - 1 Oct 2007

Toyoshima Marcos T K, Castroneves Luciana A, Costalonga Everlayny F, Mendonca Berenice B, Arnhold Ivo J P, Jorge Alexander A L

Abstract excerpt

CONTEXT: A GHR-exon 3 polymorphism has been reported to influence the growth response to hGH therapy in short stature children. None of these studies provided data on IGF-1 generation test. OBJECTIVE: To evaluate the influence of the GHR-exon 3 polymorphism on the generation test in children with idiopathic short stature (ISS). DESIGN AND PATIENTS: A total of 45 prepubertal ISS children were submitted to IGF-1...

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Source

Identifiers

PMID: 17555512
DOI: 10.1111/j.1365-2265.2007.02915.x

Genes

GHR
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Exon 3-deleted genotype of growth hormone receptor (GHRd3) positively influences IGF-1 increase at generation test in children with idiopathic short stature.PMID 17555512Read ↗

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