Article
[Relationship between the polymorphism of growth hormone receptor Ex3 and the efficacy of rhGH treatment in children with idiopathic short stature].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 1 Sept 2010
Lu Wen-Li, Wang Wei, Wang De-Fen, Xiao Yuan, Huang Xiao-Ping, Dong Zhi-Lan
Abstract excerpt
OBJECTIVE: To assess the influence of growth hormone receptor (GHR) Ex3 genotype on the short-term response to recombinant human growth hormone (rhGH) therapy in children with idiopathic short stature (ISS). METHODS: Thirty prepubertal children with ISS receiving rhGH treatment [0.116±0.02 IU/(kg/d)] were randomly recruited. The GHR Ex3 locus was genotyped using a PCR multiplex assay. The growth data including...
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