Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Growth hormone receptor sequence changes do not play a role in determining height in children with idiopathic short stature.

Hormone research - 1 Jan 2006

Hujeirat Yasir, Hess Ora, Shalev Stavit, Tenenbaum-Rakover Yardena

Abstract excerpt

BACKGROUND/AIMS: In children with short stature, in whom growth hormone deficiency has been excluded, the presence of a normal or elevated growth hormone concentration concomitant with low insulin-like growth factor I suggests growth hormone insensitivity (GHI). Previous reports suggest that heterozygous mutations in the growth hormone receptor gene (GHR) may account for about 5% of children with idiopathic short...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Height
Share to DNA
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Growth Disorders

Share to Human Growth Hormone

Share to Insulin-Like Growth Factor I

Share to Polymorphism, Single-Stranded Conformational

Share to Receptors, Somatotropin

Source

Identifiers

PMID: 16582564
DOI: 10.1159/000092514

Genes

GHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Growth hormone receptor sequence changes do not play a role in determining height in children with idiopathic short stature.PMID 16582564Read ↗

Growth hormone receptor mutations in children with idiopathic short stature.Semantic proximity Read ↗

Heterozygous mutations of growth hormone receptor gene in children with idiopathic short stature.Semantic proximity Read ↗

Analysis of the intracellular signalling domain of the human growth hormone receptor in children with idiopathic short stature.Semantic proximity Read ↗

Heterozygous GHR gene mutation in a child with idiopathic short stature.Semantic proximity Read ↗

Growth hormone/IGF-I axis and growth hormone receptor mutations in idiopathic short stature.Semantic proximity Read ↗

Mutations of the growth hormone receptor in children with idiopathic short stature. The Growth Hormone Insensitivity Study Group.Semantic proximity Read ↗

Genetic variations at the human growth hormone receptor (GHR) gene locus are associated with idiopathic short stature.Semantic proximity Read ↗

Mutation of growth hormone receptor in children with Idiopathic Short Stature.Semantic proximity Read ↗

Idiopathic Short Stature: What to Expect from Genomic InvestigationsSemantic proximity Read ↗

Idiopathic short stature: will genetics influence the choice between GH and IGF-I therapy?Semantic proximity Read ↗

The Growth Response to Growth Hormone (GH) Treatment in Children with Isolated GH Deficiency Is Independent of the Presence of the Exon 3-Minus Isoform of the GH ReceptorSemantic proximity Read ↗

Association of serum components of the GH-IGFs-IGFBPs system with GHR-exon 3 polymorphism in normal and idiopathic short stature children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.