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Article

Idiopathic short stature: will genetics influence the choice between GH and IGF-I therapy?

European journal of endocrinology - 1 Aug 2007

Savage Martin O, Camacho-Hübner Cecilia, David Alessia, Metherell Louise A, Hwa Vivian, Rosenfeld Ron G, Clark Adrian J L

Abstract excerpt

BACKGROUND: Idiopathic short stature (ISS) includes a range of conditions. Some are caused by defects in the GH-IGF-I axis. ISS is an approved indication for GH therapy in the USA and a similar approval in Europe may be imminent. Genetic analysis for single-gene defects has made enormous contributions to understanding the physiology of growth regulation. Can this type of investigation help in predicting growth...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17785695
DOI: 10.1530/EJE-07-0292

Genes

GHR
SDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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