Article
The GH-IGF-I axis in children with idiopathic short stature.
Trends in endocrinology and metabolism: TEM - 1 Oct 2002
Blair Joanne C, Savage Martin O
Abstract excerpt
Idiopathic short stature (ISS) is a term used for children in whom the etiology of the short stature is undefined. Investigations of the growth hormone (GH)-insulin-like growth factor I axis have revealed several molecular and endocrinological defects in ISS patients. Abnormalities of GH secretion and action, although not frequent, will help to categorize some children with ISS. Because most diagnostic methods...
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