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Article

The Prevalence of Transmitted Resistance to First-Generation Non-Nucleoside Reverse Transcriptase Inhibitors and Its Potential Economic Impact in HIV-Infected Patients

22 Aug 2013

Abstract excerpt

Non-nucleoside reverse transcriptase inhibitor (NNRTI)-based highly active antiretroviral therapy (HAART) including efavirenz is recommended as a 1(st)-line treatment choice in international HIV guidelines, and it is one of the most common components of initial therapy. Resistance to 1(st)-generation NNRTIs is found among treated and untreated HIV-infected individuals creating a subpopulation of HIV-infected...

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PMID: 23991151
DOI: 10.1371/journal.pone.0072784

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