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Antiviral Drug Resistance and the Need for Development of New HIV-1 Reverse Transcriptase Inhibitors

27 Jun 2012

Abstract excerpt

Highly active antiretroviral therapy (HAART) consists of a combination of drugs to achieve maximal virological response and reduce the potential for the emergence of antiviral resistance. Despite being the first antivirals described to be effective against HIV, reverse transcriptase inhibitors remain the cornerstone of HAART. There are two broad classes of reverse transcriptase inhibitor, the nucleoside reverse...

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HIV/AIDS drug development and treatment
HIV Research and Treatment
Pneumocystis jirovecii pneumonia detection and treatment

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22733071
DOI: 10.1128/aac.00591-12

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