Article
Assessing the Paradox Between Transmitted and Acquired HIV Type 1 Drug Resistance Mutations in the Swiss HIV Cohort Study From 1998 to 2012.
The Journal of infectious diseases - 1 Jul 2015
Yang Wan-Lin, Kouyos Roger, Scherrer Alexandra U, Böni Jürg, Shah Cyril, Yerly Sabine, Klimkait Thomas, Aubert Vincent, Furrer Hansjakob, Battegay Manuel, Cavassini Matthias, Bernasconi Enos, Vernazza Pietro, Held Leonhard, Ledergerber Bruno, Günthard Huldrych F
Abstract excerpt
BACKGROUND: Transmitted human immunodeficiency virus type 1 (HIV) drug resistance (TDR) mutations are transmitted from nonresponding patients (defined as patients with no initial response to treatment and those with an initial response for whom treatment later failed) or from patients who are naive to treatment. Although the prevalence of drug resistance in patients who are not responding to treatment has...
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