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Article

Coordination and processing of DNA ends during double-strand break repair: the role of the bacteriophage T4 Mre11/Rad50 (MR) complex.

Genetics - 1 Nov 2013

Almond Joshua R, Stohr Bradley A, Panigrahi Anil K, Albrecht Dustin W, Nelson Scott W, Kreuzer Kenneth N

Abstract excerpt

The in vivo functions of the bacteriophage T4 Mre11/Rad50 (MR) complex (gp46/47) in double-strand-end processing, double-strand break repair, and recombination-dependent replication were investigated. The complex is essential for T4 growth, but we wanted to investigate the in vivo function during productive infections. We therefore generated a suppressed triple amber mutant in the Rad50 subunit to substantially...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23979587
DOI: 10.1534/genetics.113.154872
PMCID: PMC3813861

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Source receipt: pubmed, retrieved 7 Sept 2026.

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