Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The CTLA-4 +49GG genotype is associated with susceptibility for nephrotic kidney diseases.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Nov 2013

Spink Clemens, Stege Gesa, Tenbrock Klaus, Harendza Sigrid

Abstract excerpt

BACKGROUND: The pathogenesis of primary nephrotic kidney diseases is not completely understood. As T-cell involvement is suspected, cytotoxic T-lymphocyte antigen 4 (CTLA-4) expressed on activated T cells could play a role in the immune response. Single-nucleotide polymorphisms (SNPs) in the CTLA-4 gene are associated with several autoimmune-related diseases. METHODS: Our goal was to study the occurrence of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to CTLA-4 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Glomerulonephritis, Membranous

Share to Glomerulosclerosis, Focal Segmental

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Source

Identifiers

PMID: 23975748
DOI: 10.1093/ndt/gft381

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The CTLA-4 +49GG genotype is associated with susceptibility for nephrotic kidney diseases.PMID 23975748Read ↗

Cytotoxic T- Lymphocyte Antigen-4 (CTLA4) Gene Expression and Urinary CTLA4 Levels in Idiopathic Nephrotic Syndrome.Semantic proximity Read ↗

CTLA-4 Polymorphisms in Patients with IgA Nephropathy Correlate with Proteinuria.Semantic proximity Read ↗

Association of STAT4 polymorphisms with susceptibility to primary membranous glomerulonephritis and renal failure.Semantic proximity Read ↗

Association of CTLA-4 gene polymorphism with end-stage renal disease and renal allograft outcome.Semantic proximity Read ↗

The relationship between the TGF-beta1 gene -509C/T polymorphism and tubulointerstitial damage resulting from primary nephrotic syndrome.Semantic proximity Read ↗

A deeper understanding of the association between CTLA4 +49A/G and acute rejection in renal transplantation: an updated meta-analysis.Semantic proximity Read ↗

Association between CTLA4 polymorphisms and susceptibility to granulomatosis with polyangiitis.Semantic proximity Read ↗

CTLA-4 +49 A/G genotype and HLA-DRB1 polymorphisms in Turkish patients with Henoch-Schönlein purpura.Semantic proximity Read ↗

TLR1 polymorphism rs4833095 as a risk factor for IgA nephropathy in a Chinese Han population: A case-control study.Semantic proximity Read ↗

The influence of CTLA-4 single nucleotide polymorphisms on acute kidney allograft rejection in Turkish patients.Semantic proximity Read ↗

Association between CTLA-4 polymorphisms and the susceptibility to systemic lupus erythematosus and Graves' disease in Thai population.Semantic proximity Read ↗

CTLA-4 SNPs (CT60A/G, -1722T/C, -1661G/A, and -318C/T) and systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.