Article
The relationship between the TGF-beta1 gene -509C/T polymorphism and tubulointerstitial damage resulting from primary nephrotic syndrome.
Renal failure - 1 May 2010
Li Y, Liu F-Y, Peng Y-M, Li J, Sun L, Chen X, Duan S-B, Ling G-H, Guo N, Liu Y-H
Abstract excerpt
BACKGROUND: The aim of this study was to investigate the correlation between the transforming growth factor (TGF)-beta1 gene -509C/T polymorphism and the susceptibility to primary nephrotic syndrome (PNS), and in particular to the severe degree of tubulointerstitial damage (TID) seen in Chinese. METHODS: Ninety-eight PNS patients and 128 normal controls were studied. The extent of tubulointerstitial changes was...
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