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Article

Association of STAT4 polymorphisms with susceptibility to primary membranous glomerulonephritis and renal failure.

Clinica chimica acta; international journal of clinical chemistry - 9 Oct 2011

Chen Shih-Yin, Chen Cheng-Hsu, Huang Yu-Chuen, Chan Chia-Jung, Hsieh Yao-Yuan, Yu Min-Chien, Tsai Chang-Hai, Tsai Fuu-Jen

Abstract excerpt

BACKGROUND: Membranous glomerulonephritis (MGN) is one of common causes of idiopathic nephrotic syndrome in adults, and 25% of MGN patients proceed to end-stage renal disease. STAT4 gene polymorphisms have been reported to be associated with many inflammatory diseases. The objective of this study was to clarify the relationship between STAT4 gene polymorphisms and the pathogenesis of MGN. METHODS: We investigated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21740896
DOI: 10.1016/j.cca.2011.06.020

Genes

STAT4

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