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CTLA-4 SNPs (CT60A/G, -1722T/C, -1661G/A, and -318C/T) and systemic lupus erythematosus: a meta-analysis.

Critical reviews in eukaryotic gene expression - 1 Jan 2014

Zhu Yun, Wang Jing, Feng Xuebing

Abstract excerpt

In this meta-analysis, we investigated the association between CTLA-4 polymorphisms (CT60A/G, -1722T/C, -1661G/A, and -318C/T) and SLE susceptibility. Data were extracted independently by two reviewers. The odds ratios (ORs) with 95% confidence intervals (CIs) were calculated in fixed or random effects models. Seventeen studies involving of 3931 cases and 4619 controls were identified. Significant association of...

Topics

CTLA-4 Antigen
Case-Control Studies
Genetic Predisposition to Disease
Humans
Lupus Erythematosus, Systemic
Polymorphism, Single Nucleotide
Prognosis
Promoter Regions, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24940764
DOI: 10.1615/critreveukaryotgeneexpr.2014007884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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