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Article

CTLA-4 +49 A/G genotype and HLA-DRB1 polymorphisms in Turkish patients with Henoch-Schönlein purpura.

Pediatric nephrology (Berlin, Germany) - 1 Aug 2008

Soylemezoglu Oguz, Peru Harun, Gonen Sevim, Cetinyurek Aysun, Ozkaya Ozan, Bakkaloğlu Sevcan, Buyan Necla, Hasanoglu Enver

Abstract excerpt

The pathogenesis of Henoch-Schönlein purpura (HSP) remains unknown; however, it is generally considered to be an immune complex-mediated disease. Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) is expressed on activated T cells, and, thus, it is critically involved in the immune response. We aimed to investigate the possible influence of CTLA-4 polymorphisms for susceptibility to HSP and determine if there...

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Identifiers

PMID: 18449568
DOI: 10.1007/s00467-008-0837-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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